Manifest Destiny re-imagines Lewis and Clark's expedition in 1804 as they're trying to explore and map out new territory. Just a comic that's a ton of fun and doesn't take itself too serious. I've read both Black Science and Manifest Destiny and I've enjoyed Manifest Destiny a whole lot more. Matter of preference I guess but it has gotten some great reviews here the last few months. I do have an affinity towards stories set during the age of exploration, discovering new worlds though. Love the innocent sense of wonder I get from Manifest Destiny.
Unfortunately a lot of Image titles will be mini series if that's not your thing. Sheltered will end on issue #15 but that's how the creators wanted the series to end. I used to be like you a few months ago where I would hate to pick up mini series and get really annoyed. I've since come full circle and don't mind them at all. Starlight is probably one of my most favorite series of all time and I would've missed out on that if I decided not to pick it up because it was a six issue mini. Also sometimes a title that starts off as a mini becomes an ongoing because of great sales and the creators want to continue to work on it.