I feel like we won't see her again soon just because of how vitriolic her exit from Peter was, if anything whatever set her up with Peter will become...
Experience is definitely more important than age although comparative to Ultimate Peter I feel like 616 Peter progressed as a hero and crime-fighter...
I guess there's a different narrative conceit comparing a younger Spider-Man doing it all on his own versus one getting into it late in the game with...
"Who wouldn't go out with the Black Widow? I'd strangle a litter of kittens for one dinner with her!"
Adrian Toomes aka the Vulture
"Natasha Romanoff, A.K.A. Black Widow - ex-KGB, formerly with S.H.I.E.L.D...Probably the brains of this operation.I have followed her career, and she has been consistently UNDERRATED."