Write a comic version of NHW

How would you go about creating a comic version of NHW? Which three comic book or other medium Spider Men would you select and what would be the storyline necessitating the crossover? I think I would select the 616 version the ultimate version and MC2 other revived Peter to represent the younger, adult and elder version of Peter to stop Mephisto and save 616 Peters daughter in the distant future from him. What are your ideas on how to go about it?

I'd use the standard 616. Cosmic Spider-man from What If. Where he has basically lost his humanity. The four armed Spider-man would be the final one.

The premise would be stopping Cosmic from destroying the Universe. By losing his humanity, he is demolishing evil, regardless of actual evil.