...And if yes, how much? Let's take both Colossus individually.
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...And if yes, how much? Let's take both Colossus individually.
MCU Spider-Man could certainly hurt Deadpool Colossus. Spidey's strength feats include his comic one of lifting the rubble of a collapsed building after being buried alive, starting from a position of nearly zero leverage. He's survived getting hit by a train. He's significantly delayed the fall of a several-thousand ton tower.
Punching Colossus would *hurt* MCU Spidey because the latter isn't made of metal, but Spidey is actually much stronger than Colossus based on feats.