Asm 700 made doc ock the new spider man. How do you think Slott will top that in asm 800?
Peter being outed as spider man. (This time without the mindwipe)
Peter/MJ reunion(with or without the marriage)
Peter starting a new tech company(not as big or successful as PI was and no doc ock and scorpio growing it from behind the scenes)
Peter returning to the bugle and using his tech skills to modernize it.
Aunt May gets killed by either Otto or Osborn as revenge
Otto will forget Peter's secret while Osborn will remember it.