That would be a definite "No" from me. I see no reason for it, and I prefer that Superman be left out of any such ideas.
I don't even want there to be another Legion cartoon unless they're going to treat it with respect and not dumb it down, like they did with the last one. The Legion deserved better than that.
Do you mean if it leads to Kara having a relationship with Brainy, or if it means her being in a non-straight relationship with another Legionnaire?
If it's the former, as a longtime Legion fan, I wouldn't mind if Kara wound up with Brainy, since there's precedent there, and it was something I felt never really was explored fully. If it's the latter, I'd say "No", because that's not who Kara has been, historically, and I don't like it when that drastic a change is made to a longstanding character "just because" with there having been nothing previously to even suggest the possibility, like what was done with Iceman.
After looking it up it turns out there IS another female Brainiac..... technically. She preferred to be called Indigo, but her actual given name was Brainiac 8.
I believe she was a villain in the first season of Supergirl.
I decided to click yes because I think that a LoSH cartoon would be good and I don't care one way or another who Clark winds up with in any given incarnation or adaptation anymore, *but* I don't watch superhero shows for romance. If it just develops over time as a natural plot point with good storytelling then great, but it shouldn't be the overarching theme or even end goal in any way. That's more suited for a live action CW or Syfy thing.
I still think it'd be hilarious to see alt-future kids of Supergirl and Brainiac show up. Coluan green skin+Kryptonian powers!
"blood drive"? *looks her up* Anyways, apparently the creators never wrote out her backstory. She looks like a female Coluan, but wears a variant of the crest of the House of El. Her known powers are similar to Supergirl's too. Apparently they never actually even named the character. She's referred to as "Brainiac's Daughter" only.
As I'm sure many others have said, we had one already. it was called Legion of Super Heroes.
Pull-List:
DC: Batman: Damned, The Green Lantern. Young Justice. Wonder Twins
Boom!: Ronin Samurai.