In the CW Network FLASH TV series, Cisco Ramon (Vibe) and Caitlin Snow (Killer Frost) have been two of Barry Allen's closest associates since the premiere episode of the show.
Ironically, in the regular continuity DC comic books, Barry hardly knows either of them. Vibe was introduced in JUSTICE LEAGUE OF AMERICA at a time when Barry had resigned from the League because he was on trial for killing the Reverse Flash. Not long afterwards, both Barry and Vibe would die (COIE and LEGENDS, respectively), without (I believe) ever having met. I'm also not sure if Barry ever met Killer Frost in the comics (especially the Caitlin Snow version, who had not yet been created).
Interesting that these three characters have been thrown together as close friends and associates on the TV series when in the comics, I'm not sure if the three have ever even met.
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