I have tons of board games (no space!) and play every week. Some of my favorites are:
- Twilight Imperium 4 - grandiose sci-fi space opera that plays in ~8 hours
- Race for the Galaxy - great role selection sci-fi themed card game
- Twilight Struggle - cold war themed war game, incredibly tense
- Lord of the Rings LCG - great with one or two players, some scenarios are extremely tough
- Puerto Rico - my favorite classic Euro board game
- Paths of Glory - my favorite wargame, covers the entire WW1
- Marvel VS 2PCG - my top superhero themed card game
- Game of Thrones 2nd edition - for fans of the the TV show this is a superb strategy board game
- The Resistance - great hidden roles party game