Edward Norton/Mark Ruffalo Hulk and Eric Bana Hulk will be teaming up to take on Josh Brolin's Thanos.
Thanos will be at his base level i.e. what he was when he beat up Hulk at the start of Avengers: Infinity War (when he didn't utilise the Power Stone).
Given that Iron Man made him bleed with four Infinity Stones in his possession and he was at least troubled in various other confrontations (including taking Stormbreaker through his chest when he had all six), can two live action Hulks end him when he has none of them?