Not impossible that's what 801 is about. Dan has said he's known the concept for 801 for awhile (or something like that) - I could see having May reveal she knows (for the third time) would definitely be a good last issue. I mean, it'd be competing against two of the more well-loved "May finds out/reveals she knows" stories (The Conversation and The Gift), so it's a bold choice, but I could see it.