There has never been a time when comics were only read by losers. Comics were hugely popular, back in the day, when they could be bought at the local corner store. They were read by lonely nerds and married men in equal measure. And, yeah, they were read by women, too, and there's letters from back then of women criticizing the handling of female characters. Superhero comics were more popular in the '60s than they are now. I will grant that Marvel and DC were better about putting out comics actually aimed at girls. They virtually abandoned that in the '90s, to focus pretty much exclusively on superhero comics, and they've never really recovered. They're both trying now - DC's Superhero Girls particularly stands out on that front - but given they spent 20 years cultivating an image of not being girl-friendly, it's an uphill battle.
I mean, I'm just going by what I've seen a lot of women say.
As for the timeline, her wearing a Spider-Man t-shirt when she's at some indeterminate age (probably 12 or 13, based on the art), and Cyclops being drawn in an anachronistic costume, are very minor complaints. They're about as petty as it gets. And hell, not even that tough to No-Prize: Unreliable Narrator. She forgot what Cyclops wore in the '60s, and she thought she was younger when Spider-Man came on the scene. Boom, done, easy. Also: That is how a true fan deals with what they see as mistakes in a Marvel comic.