I would split them up a la Hulk and She-Hulk.
Astonishing Ant-Man
Scott will be back in San Francisco facing off against tech villains like Blizzard, Ghost, Yellowjacket but the main villain would be someone he's not equipped to handle, Doctor Octopus due to him having a Pym Particle sample. The book will also have him be with Cassie in tow as Stinger or Stature and he thinks he's teaching her about superheroics when in turn it's vice versa. I would also transplant Luis in it as he recaps what happened in the last issue like the movie but the synergy will likely end there.
The Winsome Wasp
As I said, I would have Janet star with her running her fashion line and globetrotting all over the world. Nadia will be in it but only in spurts with Unstoppable Wasp running. I would have fight with Whirlwind, The Magician and other heroes but the main villain is of all people, Taskmaster! He's killing off people of royalty and one happens to near Wasp when that person is killed. Hence Janet going all over the world.