I really enjoyed this first issue. Tamaki nicely picks up where Tom Taylor left off. The Alchemax plot is still ongoing and I was growing tired of it for a while, but the inclusion of the Stepford Cuckoos has me interested again. The return of Esme and Sophie definitely shake things up a bit. If they're going to clash with X-23, it's bound to get personal. I'm looking forward to seeing where it goes.
I still wish we got some insight into why Laura is going by X-23 again. I'm hoping there's a reason behind that. Maybe it won't become clear until Logan is officially back with his new series. But I hope it comes up at some point.