The current Supreme (Blue Rose), or are you referring to Alan Moore's Supreme?
It's just the opening issue, but I thought the current Supreme was fantastic. Poetic, atmospheric, grounded in real human emotion, grand, mythological and philosophical in a way that fits with previous Supreme continuity (re-booting universes). It's strong, heady stuff with artwork that is perfectly suited to giving this universe an ephemeral, dreamlike quality. It's the best thing I've read out of Ellis in quite a while. If it holds up, it stands to be something special.
My thoughts on Alan Moore's Surpeme are that it was good, and fun, but hamfisted and preachy. Poor art did it no favors.