Considering it looks like she's got OfA, they just got to run until she drops dead a week later from accelerated aging, all white hair and wrinkles. Because the 4th user only lived 20 years with it, and that was 4 or 5 users ago (depending on whether Izuku or All Might gave it to her).
And if it WAS All Might, Izuku's dead too (suicide). Because considering how society treats those with mutation Quirks, I doubt society would be any kinder to the Quirkless.