I don't mind listing some options.
1. A comet, meteor, or asteroid could strike the earth and kill us like the dinosaurs.
2. A supervolcano could blow up half a country and plummet the world into a small ice age.
3. Nuclear war with the US vs Russia and/or China.
4. A second pandemic strikes while we're already in the midst of one.
5. More authoritarian governments rise to power.
6. More earthquakes, floods, tsunamis, hurricanes, droughts, wildfires, typhoons, and more natural disasters worldwide.
7. A terrorist attack.
8. A war, any new war breaking out.
9. Food supplies run low and many people starve.
10. A nuclear meltdown somewhere.
11. Donald Trump wins re-election.
Tons of horrid ways this year can get worse. All that was off the top of my head.