Originally Posted by
Ezyo1000
Assuming that they are already developed and powered with nen or nen-like powers in the MU, then yes it would be a tougher fight, however not something that Tchalla and Wakanda couldn't handle. One thing I think is interesting about these characters is that it would really highlight T'Challas specialty, which is prep and using unorthodox method's hut the big thing here is that Wakandan tech is more advanced then anything in the hunter x Hunter world, and after analysing how their power works, I think the killing blow would be a modified nullifying weapon to stop their power from working.
Given knuckles ability to cancel out the use of nen with his ability, this is definitely possible to make a weapon to mimic that. Ultimately this could be an event like secret invasion, where I think Wakanda would be able to hold their own whereas the Avengers and like would have a harder time for their eventual win