I think it would depend how you spin it.
I mean, I don't find Tomoe a very complex villain, but I think there is something there about a young woman coming into her own with her powers and trying to take power and carve out her own niche as a Kingpin type, and how that could potentially reflect on Miles' journey. And then you have that potential romantic attraction there that a lot of fans apparently latched onto.
Although I think she'd be more fitting for a solo movie then a Spider-Verse movie.
I wonder if they could even use Murdock. Kingpin is kind of a murky area but would they need to have Marvel's permission to outright feature Daredevil, even if he's not really Daredevil?Murderdock, and especially the Jefferson Scorpion, I think would be great since this film really delved into Miles' relationship with his father, so getting to see him face off against a version of his dad that went full on crime boss could be very powerful storywise. And Murderdock could represent the danger of the Kingpin throughout the multiverse no matter who it is.
Not all that hard in my opinion .