Depending on type and how many Pokemon you have, a lot of a damage can be dealt. Clever application of different types of attacks, like using fire and ice to make something brittle, could be possible strategy. Using the anime as a guideline isn't recommended as power levels and durability flux depending on the situation and what the plot calls for. For example in the Sinnoh seasons Ash battles his rival Paul a few times, only beating him at the Pokemon League. Even then it's very close with Ash's Infernape, which is very powerful (its main character arc is about getting control of its Blaze ability which increases power) being worn out after defeat Paul's final Pokemon.