"I want to start following Batman or Superman but they are on issue 12,483. I can't get involved now. I have to start at number 1 or I won't know what's going on."
Go to the comic store. Buy the current issue of whatever book you're interested in. Then go from there. Problem solved. You don't need to know what has happened in the book for the last 20 years.
How can we convince potential new readers that it's perfectly fine to start with #496?