Mega Man takes on the Spider-Bot mech from the new Spider-Man: Into the Spider-Verse film (just got finished seeing it today).
The Spider-Bot gets all of its weapons, while Mega Man gets his Robot Master weapons from Mega Man 11: Gears of Destiny, the Rush Jet, and unlimited usage of the Double Gear system (in other words, no overheating).
The fight takes place about 1800 yards from Dr. Light's laboratory.