Kaine is probably the closest comparison on the level of Peter getting on better terms with someone who screwed his life over, but it's also an entirely different relationship and dynamic because of the cloning thing.
Maybe if this was the Otto who gave him his body back, but this is the Otto who ended up screwing him over in Spider-Verse and joined Hydra.
I would think he'd know well enough from the last Superior escapade how Otto's attempt at heroics eventually end up.