If a Kamala series were to be standalone with no hints or ideas of connecting to a wider universe of other shows, then that kind of format I believe can work. Especially if it's an animated series.
This upcoming Disney+ one though...with it being a mini series of likely less than 10 episodes as a starter, it probably will be very basic with worldbuilding and all that, especially since there's the intention of getting Kamala into the films too. If the Disney+ series were to have multiple seasons, then yeah it can go hogwild with doing whatever it wants in adapting their own versions of the comic arcs or doing their own thing.