She could also run for another office.
There's a prominent young congresswoman in New York City.
Nick Spencer one ran for City Council in Ohio.
https://www.bleedingcool.com/2017/05...nati-politics/
I wouldn't bet on MJ getting involved in politics, since that's likely to cause headaches. On his Captain America, Spencer was hit from the right for being a Democrat and from the left for being too centrist.