Which in retrospect was why Mary Jane's Aunt Anna's depiction in TAS was so aggravating. Not only was she pointlessly hateful and bitter toward Peter despite the fact that he was her best friend's nephew and the love of her niece's life, it completely flew in the face of how much respect she had for him in the comics as basically the one man in Mary Jane's life who genuinely loved and cared about her and went out of his way to make her happy. Granted, there was the time Anna suspected all of Peter's bizarre and half-explained absences were the product of an affair, but at least that was a reasonable conclusion some people could come to without knowing that he was Spider-Man, as opposed to just hating him from the get-go no matter what.
Also, speaking of MJ and her family, I'd love to see more of them show up in the comic, or at least get an explanation as to whatever happened to them now that she and Peter are back together and she's coming off a stint working for Tony Stark, of all people.