Purp.. no. Best chance at this moment is a producer and that's not happening. KF has all his people lined up in house. If he wants to be a director he's going to have to cut his teeth. Disney is too powerful now, they aren't going to give first time directors a chance on any of their films. Channing might be able to pull off early 30s. Late 20s if he drops like 30lbs or more. That would make Gambit the elder statesman of the X-Men ie the responsibile one, like how they did with Wolverine in Evolution. I don't want that kind of Gambit.
I don't know who'd play him at this point but I'd still like to see the character opposite a Jamie Foxx played Bishop. I think that'd be fun.