spoilers:end of spoilers
First things first Gwen goes with Harry to visit Dr. Elsa Brock only to find out she's gone. Her office is abandoned, her name's not on the database and basically it's like she never existed. Really though, what did Gwen expect? Norman wasn't happy when he found out Elsa was working for the Kingpin so no shit she wouldn't be working there anymore. Did she think the non-criminal (apart from some tax evasion) Norman would really let her stay?
Incidentally, Gwen confirms that Matt Murdock is in fact in prison. Oddly she mentions her and Evil Cindy Moon and only comments on the prison bit to explain why they can't help her. Thing is, why the hell would she think that they would help her even if they could? Hell, why would she think Elsa would help her? Gwen was against all three of them and two are in prison because of her! Why the fuck would she think they would help her even if they weren't confined? Hell, why doesn't she mention Cap and SHIELD in general? This is just bizarre.
Anyway, we see later on that, yes, the symbiote is making her go cuckoo crazy. Not only are spiders spilling out everywhere but she's much more brutal with beating on thugs. Sadly one of her spiders stays in said thug at which point Miles Warren gets a sample of it. Oi vey, Earth-65 Clone Saga here we come!
We also get the context of MJ being such a bitch...and it's weak. The idea seems to be that she's really stressing out and wants the comeback gig to be perfect as perfect can be. And no, this in no way justifies her choice of insults of calling Gwen an attention whore or screaming that she doesn't care about the band.
Anyway, we finally get to the gig and someone rigged it with bombs. Yes, bombs plural. Gwen's able to block the stage with web but the crowd is fucked and explodes. Yeah, pretty sure at this point the band is dead. Their comeback gig literally started off with a bang and there's no way they'd ever be able to recover from this. Just another thing not tying Gwen to Earth-65 anymore...
On a non spoiler note, Gwen has...interesting choices in fashion. Either she doesn't get the context of the design or she's just being really morbid:
Also, apparently Gwen being a part of the Mary Janes isn't public knowledge? She definitely surprised people when she transformed:
Kinda surprising considering how InFamous she is. You'd think people would know that.