Marvel has cancelled their entire line of books since the New 52 started, and most of those titles more than once.
Of course, if you don't consider cancelled books being cancelled, then I don't know what to tell you. Hopefully you're not counting titles like Justice League International, Batman: The Dark Knight, Suicide Squad, Nightwing. Teen Titans or Deathstroke in DC's cancelled book numbers then. In fact, how many Marvel titles would you say have been cancelled in the last three years?