So there's an in interesting trend I've noticed about femme fatale supervillainesses who transition into being heroes or antiheroes. Namely, that they become more "action" oriented instead of or in addition to being seductive and manipulative
Emma Frost went from a villainous, scantily-clad telepath to an antihroic, scantily-clad telepath who could turn her skin into diamond. I also recall an issue of Generation X had her taking up boxing.
Poison Ivy as a villain relied on poison kisses and pheromones. Ever since she's been written in a more sympathetic or borderline heroic light, she's been turned into a plant goddess of sorts.
Black Widow in her first appearances as a villain was mainly just a seduction agent who relied on incompetent minions to handle the violence. Ever since she became a hero, she's been written as a deadly action hero with combat skills and powers on par with Captain America.
The comic book version of Jade Nguyen aka Cheshire is your standard dragon lady femme fatale who relies on poisons and sex. Her Young Justice animated counterpart is depicted as a competent martial artist.
Catwoman as written by Tom King is one half of a battle couple with Batman and bested Talia al Ghul (a woman trained from birth as an assassin) in a sword fight.
Black Cat as a hero had cat based superhuman strength, speed and agility. Her 90 cartoon counterpart had a variant of the super soldier serum that turned Steve Rogers into Captain America.