Mutants of course tend to have mutants....with the odd fluke like Graydon Creed.
Spider-Man has had multiple futures where his kids have had spider mojo.
Spider-Woman's son Gerry go it going on as well.
Nick Fury passed on the Infinity Formula to his son Nick Jr.
Reed and Sue getting their genetics jacked up by Cosmic Rays led to one of the most powerful mutants being born....still waiting to see if Val gets something as well....would love to see her have her Mom's powers.
So...what can be passed on....aside from "whatever the writer wants"