I don't think this comic presents is as the symbiotes affecting his mind though. For one thing, as his conversation with Reed goes, he is choosing to use the Symbiote despite knowing it's alive (when originally the first thing Peter does on finding out is ejecting it and then using the cloth version of the costume). He puts MJ in a difficult situation of (as far as she knows) potentially killing her husband and father of her children. He ejects the symbiote in that fight with MJ when she calls out that its addictive, and then goes to blow off air abandoning MJ and the kids. Then he gets buried by Kraven, the symbiote then activates and MJ chases after him with that scanner to find her husband becoming a Venom monster (and Venom's first appearance in comics is terrifying the bejezus out of MJ and the trauma of that leading MJ to insist immediately that Peter never wear the black costume again and go back to red-and-blue). Then after it ejects and loses the symbiote, Peter passively accepts MJ leaving with the kids. Peter also says to Reed that he uses the suit because it helps him but then adds, "to stay relevant" which means that this is about some kind of early mid-life crisis more than anything.
The evidence is clear. Life Story Peter is an asshole, plain and simple. It was building up from Issue #1 like him starting that needless argument with Flash to get a rise at him, him laying out at Reed Richards and insulting him for Sue leaving him, and now here. It's not about doing what's right for his family, or doing right as a superhero, he's just a passive-agressive prick. That interpretation of Peter is certainly valid, and being openly presented that way rather than the crappy both-ways-excuses that OMD-OMIT tried to do it is better.