So a pretty decent issue I must say, which did a great job at setting up the after effects of Hunted.

spoilers:
On a side note, Gwen Stacy, or at least a Gwen clone, definitely rose on my list of suspects after this issue, as the identity of the mysterious Centipede character. The way he/she describes Peter failing to save people close to him, that he's a danger to them, and that he/she wants to be together with Peter does at least hint that whoever Centipede is, they possibly might be a former love interest who Peter failed to save.

Also the return of the Savage Six and Chameleon! Yes!
end of spoilers