Howabout :

Sony Logo. Villain introduced . Kraven introduced? (Maybe Sasha Baron Cohen or "Freddie Mercury " guy?). Plans to hunt spidey...

Marvel Studios logo - Emotional "Leave Spidey alone" home video made by Flash Thompson ("NO WAY is he Peter Parker!")

Elderly Cap in supporting role?

Formation of Sinister 6

Tech-guy William using Mysterio holograms?

Pepper shows up with Riri Williams as her progeny. (flashback scenes of young Riri using homemade suit to keep peace during post-snap disorder)
Possible competition for MJ...

Miles Morales shows up. Bryan Cranston as head of Oscorp Norman Osborn

and YOUR ideas?