Hannah Conover was introduced in the Brood: Earthfall storyline, in Uncanny X-Men #233-235 in 1988, and reappeared in the miniseries Day of Wrath, in 1996.
She was the wife of a traveling preacher, and suffered crippling arthritis, until the arrival of a starshark on Earth, carrying a small contingent of the Brood. These Brood began hunting and infecting - as they are wont to do - and even infected several mutants, in what I believe was the first indication that the Brood can take on the preternatural abilities of their hosts. Hannah was infected with a Queen, and her arthritis cleared up rather 'miraculously', which led to her becoming a faith healer...who infected those seeking healing with a Brood embryo.
Rather unexpectedly, her faith caused her - and her spawn - to rebel against the hateful, genocidal wishes of the Empress - the closest thing we've seen to a Brood deity - which caused the Empress to send her Firstborn, elite Brood warrior assassins, to kill Hannah and her rebel Brood. This led to the X-Men discovering what Hannah had become after their last encounter, and also led to the revelation that, in Bishop's time, there were rumors of a Brood hive that served the side of good and right. This led the X-Men to do some soul-searching, and eventually to pledge their support of Hannah and her spawn against the Empress.
At the end of the Day of Wrath storyline, everyone realized that the Empress would continue sending Firstborn to Earth until Hannah was eradicated, as the thought of a Brood nest that didn't serve the Empress was too dangerous to be allowed to run free. All of Hannah's spiritually-inclined, 'independent' Brood died keeping her safe from the Firstborn, battling alongside the X-Men, and the X-Men put her in stasis beneath the mansion to fool the Empress into thinking the Rogue Queen was dead, which led to the remaining Firstborn killing themselves, as the threat Hannah represented to the 'purity' of the Brood was gone, or so they thought.
And...then nothing. The mansion got 'sploded a few times, the X-Men moved to San Francisco, Wolverine returned and opened a school on the ruins, the school went to Limbo for a while, then Central Park, then Krakoa...
We got Broo, a free-willed, mutant Brood, in the Wolverine & the X-Men run, which would have been a PERFECT time to reintroduce a free-willed Queen. But nope. Will we ever see her again? Is this plot thread gonna dangle in the wind forever? Is anyone else interested in seeing what comes next? What say you, CBR?