Any Favorite Spiderman Single Issue/ Stand Alones worth reading?

[Batman Begins 2005]

Amazing Fantasy #15.
The Kid Who Collects Spider-Man. The Amazing Spider-Man (Vol. 1) #248.
Peter Parker: The Spectacular Spider-Man (2017) #6.
Peter Parker: The Spectacular Spider-Man #310.
The Conversation. The Amazing Spider-Man (Vol. 2) #38.
Confessions. Ultimate Spider-Man #13.
The Amazing Spider-Man #400.

[K7P5V]

A couple of the Graphic Novels are great. Spirits of the Earth & Hooky both take Spidey out of his comfort zone, but are great.

If you're a fan of the Peter & MJ relationship, I recommend Parallel Lives and To Have And To Hold (Sensational Spider-Man Annual #1).

Zdarksy's last issue on Spectacular is also really great.

Great choices. I would also add "All My Pasts Remembered!" from Amazing Spider-Man #259, which is highly recommended.

The Amazing Spider-Man Annual #19 is my second favorite.

The Amazing Spider-Man Annual #28 is my third favorite.

Here's how I rank my top three (3) favorite ASM Annuals:
1. "Fun 'n' Games" from Amazing Spider-Man Annual #19
2. "Man of the Year" from Amazing Spider-Man Annual #20
3. "The Wedding" from Amazing Spider-Man Annual #21

[David Walton]

Roger Stern's "The Daydreamers" is maybe the greatest single issue of any Spider-Man comic.

"The Daydreamers" is criminally underrated.

[Revolutionary_Jack]

"The Daydreamers" is criminally underrated.

It's Stern's own favorite of his entire run. If you want to know Spider-Man and his supporting cast and why they all share the same story thematically, that one issue tells you everything.