Well a counter to that is Liv Octopus from ITSV, she's a total gangster-thug mad scientist and a lot of people say she's better than Molina's Ock (and I agree).
In Spider-Man 2, Otto has no character and personality, merely being a puppet to the AI in his tentacles. He effectively is two characters. The kindly Otto from before, and the Doctor Octopus of the Tentacles. The AI Doctor Octopus is essentially the character from the comics -- a gangster thug and terrorist. The Doctor Octopus in the train sequence, the nutcase who robs the bank while smoking a cigar and so on, is classic Ock, and not at all the sympathetic version of the character. And that ultimately is what people took home. Nobody thinks that the best scene with Dr. Octopus in Spider-Man 2 is the one before the transformation where they discuss T. S. Eliot, the one everyone wants is the dude in the train sequence who terrorized the passengers, driving them to try and defend Spider-Man from him....as seen in like Spider-Man 2, the PS4 game, and even Superior itself,
The PS4 has sympathetic traits a la Walter White and so on, but eventually the character becomes a classic white terrorist who unleashes a bioweapon on a civil population. In Superior, Otto is a terrorist who tried to burn the world in ends of the earth then hijacks and vampirically feeds of a much younger man and...is pardoned for it, and that's paraded as a redemption arc. What that speaks is the endless ways domestic terrorists and white criminals are "humanized" and given "Redemptive arcs" in a way that would never have been done if the characters were of any other ethnicity. That was made clear when Zdarsky wrote LIFE STORY #6. Octopus hijacking Peter is played as "Freaky Friday", Otto hijacking Miles is "Get Out" and treated that way.