As a huge ATLANTA fan, during the episode with the German festival I realized she was the baddest woman on television. Not a fan of Deadpool in the least but yes, an argument can be made for her being well in the top 5.
Damn shame Yvonne Craig (RIP) hasn't been mentioned. I was in the third generation(? in the 80's) of repeats for the Dozier Batman show and even then, if her Batcycle didn't roll past in the opening credits it was a pass on that episode. 70's Wonder Woman reruns didn't come around nearly as often as 60's Batman, Craig was the Alpha.