Maddie definitely should show up. Afaik her, Shadow King and Cassandra Nova are the biggest villains not invited on Krakoa.
Finished my 2nd reading and on top of the Nimrod tease, the way Orchis is described is very reminiscent of Project Nimbus or whatever they called the hivemind of Earth best humans in Life 6. Narration call the scientifics minds a weapon and Karima calls Orchis an experiment.