I can easily see it because as we all know, Latveria was one of the the few countries the rejected the trade deal for "political reasons". I don't think they would've noted that if it meant nothing. Besides, I don't think Doctor Doom of all people would stand idle to the idea of the world belonging to mutants (or really, anyone but him). I imagine that Doom would think "This world belongs to Doom, and not mutantkind!". Not sure if he explicitly hates mutants or not, because there have been indicates that he does, yet other times he doesn't, but even still. If anyone is going to take action against the idea of the world belonging to an outsider race, it'll be Doom. Plus, this whole saga is penned by Hickman, and Doom was the ultimate final villain of his landmark Fantastic Four/Avengers run.
If it comes to Doom opposing Krakoa, what do you think? Furthermore, how do you think it will happen? I can see him gearing up Latveria, and striking an uneasy alliance with others, as preparation for war. Then of course, he begins his chessmaster schemes that all work in his favor while disrupting the mutant nation.
Discuss.