According to the solicitations for January's Amazing Spider-Man, something called "Last Remains" is coming and the build-up starts with Issue 37.

Bleeding Cool thinks the timing of the launch of a satellite book is going to be based on that story.

So, what do you think "Last Remains" could be?

It does seem like it could be part of the 50th issue (unless the book goes back to ASM's original numbering with #850)