My favorite silly plot arc took a couple of *years,* if I recall correctly, to resolve, and it was that of Lytton Synge (I may be horribly misremembering his name...). In the very first issue he killed off his dad to inherit his casino empire, and framed Xian, leader of the X-Men, for the murder. He got played by his sister and mutated into a hulking monstrosity that finally broke free and tracked down one of the X-Men (and his sister, Desdemona?) at the top of the tower that he once (briefly) ran, climbing hand by hand up the skyscraper to get his much-anticipated revenge.
Unfortunately, Doom was present, having just announced that he was taking over, and the Hulk-monster-Lytton interrupted him. Without turning around, Doom casually blasted him off the roof, to fall a hundred stories to his presumed death. Doom then continued speaking, as if nothing had happened.
And that ended the *two year* story arc of his revenge.
I loved it.