The Spider-Geddon written by Chris Gage (who was on the writing team of the first game) had the Spider-Man PS4 version participate in that Spider-Verse event and he appointed Miles Morales to step up while he's away in the Spider-Verse.
So maybe this could be that, if they want to do synergy. Alternatively they could say Peter's doing some Avengers stuff (since they are established in the shared universe).
I think Peter Parker will be in this game though in some capacity, though.