Oh gosh, there's tons. You could make an all-mutant 'Latin League' if you wanted...
El Aguila
Defensor (dead?)
Sunspot
Magma / Amara (not sure if she counts, she's from South America, but who knows if she's originally of Italian stock or not...)
Empath / Manuel de la Rocha
Darwin
Skin (dead)
Goldballs
Cecelia Reyes
Rictor
Wind Dancer (depowered currently)
Velocidad
Risque
Ghost Rider/Reyes
Satana
Silverclaw
El Toro
Firebird
Living Lightning
Reptil
Spider-Girl/Arana/Anya Corazon
Spider-Man/Miles Morales
America Chavez
Echo/Ronin/Maya Lopez
Victor la Mancha
Power Man/Victor Alvarez
Poison
White Tiger/Ava Ayala (currently depowered)
White Tiger/Angela del Toro (currently depowered)
I'd love to see more of Aya Ayala/White Tiger and Wind-Dancer repowered, along with Living Lightning, Reptil, Sunspot, Goldballs, Cecelia Reyes and Spider-Girl/Arana.
There are others I'm sure I'm forgetting, or less sure about, like Wraith (Hector Mendoza?) and maybe Microbe, or the Cortez siblings, or Carmella Unuscione, or her half-brother Radius, or la Bandera (who I think is also dead, and I only know from her Marvel RPG stats in an old issue of Dragon magazine)?
Some of them are kind of cheating. Victor la Mancha is a robot, but grew up thinking he was a Latino human, so I'm fine with him, but America grew up in another dimension full of super-ladies and, AFAIK, no concept of ethnic groups, so I'm not sure she really 'counts' any more than Martian Manhunter shapechanging into a black man 'counts' as African-American representation. Same with Amara/Magma, growing up in Nova Roma, thinking of herself as part of a lost Roman outpost, doesn't really scream 'the latino experience' to me. (But what do I know?)