It does reminds me of the beginning of Wolverine #98 especially with Logan awakening in the middle of a carnage where several of his friends are dead and believing he's the one who did it:
If I'm not mistaken, Omega Red's condition was stabilized in the Wolverine Origins series when he finally recovered the C-Synthesizer. After his resurrection in X-Men Gold, he had to feed on people's life force to stay alive at first until Magik was forced to stabilize his condition once and for all, I don't remember if he had any problem with his powers during the recent Weapon X series though especially when it comes to his death spores. I remember that he has been able to use them at will in the past.
With that said, when it comes to the relationship between the C-Synthesizer, the carbonadium's radioactivity inside Omega Red's body and his death factor, things have been really contradictory through the years to the point I'm not even sure what's true and false anymore lol.
What's more worrying about Omega Red is the fact that he's a damn psychopath and a serial killer who kidnapped and killed several young girls before being turned into a super-soldier. Thinking about it, I do wonder if Banshee will show up especially after what Percy said about Omega Red and what's going to be his role in this story.