Looking back, I find it harder to watch all 22 episodes of the X-Files for certain seasons. I find that there are a few episodes that I love so much that I'd just jump right into those ones. Episodes like D.P.O, Pusher, Rush are ones that I think I can watch over and over. However, some of them are pretty hard for me to get through.
It's weird about 24, because I thought season 3 was alright...absolutely hated season 4, but I'm glad I stuck around for season 5 as I think season 5 is the best season of 24. That includes the 1 and 2, which were both pretty intense, IMO.
As for me? I watched season 6 and 7, but I could have sworn I heard or read somewhere that Eric Kripke wanted to make Supernatural a 5-season show (Mandela Effect, maybe?). When season 4 hits, you can tell just how epic a scope Kripke wanted to work on and I was just absolutely psyched when season 4 ended and how season 5 began. Then the show got so popular that it couldn't have an end point. I hated most of season 6 and 7, but after 7 I was like "Yeah, this show should have ended after season 5"
To this day, I honestly hope someone does an HBO-type take on Supernatural, where the scope can be world-spanning, rather than just across the US. Then again, I wonder how much of the appeal of the show would be lost. Supernatural really caught onto something...special, IMO. The chemistry between Ackles and Padelecki is undeniable. The whole concept of driving around from place to place in an Impala is just damned cool and the show really was about exploring urban supernatural myths in the US.
I recently watched season 1 of Supernatural and just jumped right ahead to season 4 and finished it off with 5. Just some absolutely awesome TV, IMO.