What is the most effective combination of Infinity Stones? (616)

[Shellhead]

The Infinity Stones have been around in the 616-universe long enough to rack up some feats. We all understand that the combined power of all six stones is a huge threat in the 616 universe, with a synergy far beyond the abilities of the six separate stones. But which stones have the most effective synergy if a character could only wield two of them? My guess would be Reality + Power, but maybe the reality alteration comes up short without certain other stones, like say Mind or Time.

[The Drunkard Kid]

IIRC, the Reality Gem is super difficult to use without the other Gems as well. I seem to recall Thanos needing a massive machine in order to do so, or something along those lines.

[The Chou Lives]

All together is the best duh.

Honestly the triple threat of Mind, Time, and Space is good.

[big_adventure]

Reality and Power is the goto combo. Reality is meh by itself, Power makes it feasible.

[KJS]

All together is the best duh.

Honestly the triple threat of Mind, Time, and Space is good.

Both statements are slightly insignificant when the question was "which two?"

But anyway, depending on the aim of the wielder, I think you can split them up into three pairs and get equal success: Time and Space, Reality and Power, Mind and Soul.

[The Chou Lives]

I would go with Mind Soul if just two or Mind/Time. The Soul combo means you can access all brains in universe, telekinesis, and soul allows you to grant yourself super powers.

The Time/Mind one is like being a shraingian ninja from Naruto.

[LordMikel]

I'm thinking space and Mind. I can be anywhere I want to be and I'd be able to read people's minds.