It seems like the end of Last Remains is going to be the all-hope-is-lost portion of the overall arc Spencer is writing here. If MJ does die and everything is seemingly off the table, the big conclusion with a rematch against Kindred could be Peter fighting his way through hell to save MJ and bring her back. I dunno. There's two Spidey supporting characters I don't ever wanna see die cause they're so great and they're MJ and JJJ haha.