This is only true if the only reason you are connecting with a certain character is their allegorical relationship to 1 specific topic. Further, these are comic books not an academic dissertation, generalization is strength not a weakness. Anecdotally, I would argue that people come for the claws and laser beams but stay because they made a connection to a character or theme. The X-Men are built on themes of "persecution" and "otherness", feelings that are generally relatable regardless of the readers own specific circumstances.. You could just as easily argue that your examples are so specific as to be a turn off unless the reader wants to cover that specific theme.