Not in Orlando. The Guardians ride is replacing the Tower of Terror in Anaheim. Per the contract in place with Universal Studios and Marvel from the 90's when Marvel was selling IP's to keep afloat, Universal has sole rights to the Marvel characters East of the Mississippi in their parks. That is why there will never be a Spider-Man, Captain America, or Wolverine in the Orlando parks. However, they can appear in all other Disney parks across the globe, and are particularly highlighted in California.