Don't think it would. Comic shops order a lot of #1s from a new series, especially popular ones. That would offset any collectors I think. It is why there is such a massive drop off in orders from issue #1 to #2. Variant covers play a part, but also the shelf life of a new #1 issue for a series is a lot longer than for some random # in an ongoing title. Since shops can sell that #1 a lot easier over time and it also has the highest chance to go up in value over time too. So there is a lot more incentive to over order for a new #1s than over order for something like Nightwing #78 even if it got a new creative team. But Taylor's Nightwing run selling out for two straight issues is really good. It doesn't even look like Bendis' JL did that.